4-(4-Chlorophenyl)piperidin-4-ol

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4-(4-Chloro­phen­yl)piperidin-4-ol

In the title compound, C(11)H(14)ClNO, the piperidine ring adopts a chair conformation: the hydroxyl substituent and the N-bound H atom occupy the axial positions, while the benzene ring occupies the equatorial position. In the crystal, the mol-ecules are linked into a centrosymmetric tetra-mer through strong O-H⋯N and weak N-H⋯O hydrogen bonds; the N and O atoms act as both donor and acceptor ...

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3-(4-Chloro­benzo­yl)-4-(4-chloro­phen­yl)-1-phenethyl­piperidin-4-ol

In the title compound, C(26)H(25)Cl(2)NO(2), the piperidine ring adopts a chair conformation with a cis configuration of the carbonyl and hy-droxy substituents. The dihedral angle between the aromatic rings of the chloro-benzene groups is 24.3 (2)°. The phenyl ring forms dihedral angles of 59.4 (3) and 44.1 (3)° with the benzene rings. In the crystal, mol-ecules are linked by inter-molecular O-...

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Synthesis, Radioiodination and Biodistribution Evaluation of 5-(2-amimo-4-styryl pyrimidine-4-yl)-4-methoxybenzofuran-6-ol

This study describes the organic synthesis of 5-(2-amimo-4-styryl pyrimidine-4-yl)-4-methoxy benzofuran-6-ol (SPBF) as an example of a benzofuran derivative used as a new series of amyloid imaging agents. These benzofuran derivatives may be useful amyloid imaging agents for detecting B-amyloid plagues in the brain of Alzheimer’s disease. The precursor is 1-[6-hydroxy-4-methoxybenzofuran-5-yl]-p...

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4-(4-Meth­oxy­phen­yl)-2-methyl­but-3-yn-2-ol

The mol-ecular structure of the title compound, C(12)H(14)O(2), features a nearly coplanar arrangement including the aromatic ring, the C C-C group and the ether O atom. The maximum deviation from the least-squares plane of these ten atoms is 0.0787 (8) Å for the ether O atom. In the crystal, mol-ecules are connected via O-H⋯O hydrogen bonds (involving the hy-droxy O atom both as hydrogen-bond ...

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1-[(4-Bromo­phen­yl)(morpholin-4-yl)meth­yl]naphthalen-2-ol

The title compound, C(21)H(20)BrNO(2), was obtained from a condensation reaction of 4-bromo-benzaldehyde, 2-naphthol and morpholine. The mol-ecular conformation is stabilized by an intra-molecular O-H⋯N hydrogen bond, closing a six-membered ring. The dihedral angle between the naphthalene ring system and the benzene ring is 76.72 (8)°. In addition to the intra-molecular hydrogen bond, the O-H g...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2010

ISSN: 1600-5368

DOI: 10.1107/s1600536810004216